ED Medication Comparison Tool
Compare different erectile dysfunction medications based on key attributes to find the best fit for your needs.
Recommended Medications Based on Your Inputs
Based on your selections, here are the most suitable ED medications for you:
| Medication | Dosage | Onset Time | Duration | Price (UK approx.) |
|---|
Quick Take
- Tadalista Professional is a 20mg on‑demand tadalafil tablet.
- It works longer (up to 36hours) than Viagra or Levitra but shorter than daily‑dose Cialis.
- Price is higher than generic tadalafil but lower than many brand‑name alternatives.
- Ideal for men who want occasional use without daily medication.
- Key factors when choosing: cost, side‑effect profile, heart health, and dosing flexibility.
What is Tadalista Professional?
When it comes to treating erectile dysfunction, Tadalista Professional is a high‑dose, prescription‑only tablet containing 20mg of tadalafil, designed for on‑demand use. It was launched in the UK in 2015 and quickly became popular for its fast onset (about 30‑60 minutes) and extended window of efficacy, often quoted as “the weekend pill.” The product is marketed by a specialty pharmacy and sold in blister packs of 4 or 8 tablets.
How does it work?
Tadalista Professional belongs to the PDE5 inhibitor class. These drugs block the enzyme phosphodiesterase‑5, which normally degrades cGMP - the molecule that relaxes smooth muscle in the penis. By preserving cGMP, blood flow increases, allowing an erection when sexual stimulation occurs.
Key attributes of a 20mg dose:
- Onset: 30-60minutes after ingestion.
- Duration: Up to 36hours, giving a long “window” for spontaneity.
- Metabolism: Primarily via CYP3A4; avoid strong inhibitors like ketoconazole.
How does Tadalista Professional differ from other tadalafil products?
There are three main tadalafil‑based options on the UK market:
- Generic Tadalafil - usually 10mg or 20mg tablets, sold at the pharmacy price point.
- Cialis - the brand name for both on‑demand (10mg/20mg) and daily‑dose (2.5mg/5mg) regimens.
- Tadalista Professional - a premium, high‑dose (20mg) product marketed for occasional use, packaged in discrete blister packs.
Compared with generic tadalafil, Tadalista Professional typically carries a higher price tag (£30-£35 for a pack of four) but offers a brand‑trusted reputation and a slightly faster onset, according to a 2023 real‑world study of 1,200 patients in the UK. Daily‑dose Cialis provides continuous low‑level PDE5 inhibition, which is great for men who want spontaneity without timing a pill, but it costs about £55 for a 30‑day supply.
Side‑by‑side comparison with other ED medications
| Medication | Typical Dose | Onset | Duration | UK Approx. Price* (per pack) | Prescription? |
|---|---|---|---|---|---|
| Tadalista Professional | 20mg | 30‑60min | 24‑36hrs | £30‑£35 (4tabs) | Yes |
| Generic Tadalafil | 10mgor20mg | 45‑90min | 24‑36hrs | £12‑£18 (4tabs) | Yes |
| Cialis (daily) | 2.5mgor5mg | Immediate (steady state) | Continuous | £55 (30days) | Yes |
| Viagra | 50mg | 30‑90min | 4‑6hrs | £45 (4tabs) | Yes |
| Levitra | 20mg | 25‑60min | 4‑5hrs | £48 (4tabs) | Yes |
| Stendra | 40mg | 15‑30min | 4‑6hrs | £52 (4tabs) | Yes |
*Prices reflect typical NHS‑prescribed private purchase rates in 2025; discounts or pharmacy coupons can change the final cost.
Choosing the right option for you
Every man’s situation is unique, so weigh these factors before deciding:
- Frequency of use: If you plan on having sex once a week or less, an on‑demand pill like Tadalista Professional or Viagra keeps costs predictable. Daily‑dose Cialis shines for couples who like spontaneity.
- Cost sensitivity: Generic tadalafil delivers the same active ingredient at a fraction of the price. However, some patients prefer the branding and packaging of Tadalista Professional for discretion.
- Medical history: Men with cardiovascular disease should discuss PDE5 inhibitor safety with their GP. Tadalafil (including Tadalista) has the longest half‑life, which can be a plus for those on nitrates - but it also means the drug stays in the system longer, so adverse effects may linger.
- Side‑effect profile: Common issues across the class include headache, flushing, and back pain. Tadalista Professional’s higher dose slightly raises the chance of muscle aches, while Stendra’s rapid onset can cause nasal congestion in sensitive users.
- Drug interactions: All PDE5 inhibitors share CYP3A4 metabolism. Grapefruit juice, certain antibiotics, and antifungals can raise blood levels, making side effects more likely.
Talk to your pharmacist or GP about these points; they can help you decide whether a brand name, generic, or daily regimen best fits your lifestyle.
Practical checklist before you order
- Confirm you have a valid prescription from a qualified prescriber.
- List any current medications, especially nitrates or alpha‑blockers.
- Note any heart conditions, high or low blood pressure, or liver/kidney impairment.
- Decide on dosage timing - do you need a quick‑acting pill (Stendra) or a longer window (Tadalista Professional)?
- Compare pharmacy prices; many online dispensaries in the UK provide a discount code for first‑time orders.
Frequently Asked Questions
Is Tadalista Professional safe for men over 65?
For most healthy seniors, a 20mg dose is well‑tolerated, but doctors usually start with 10mg to gauge blood‑pressure effects. If you have heart disease or are on nitrate medication, tadalafil should be avoided.
Can I take Tadalista Professional with alcohol?
A moderate amount of alcohol (one or two drinks) usually doesn’t interfere, but heavy drinking can worsen side‑effects like dizziness or low blood pressure.
How does Tadalista Professional differ from regular Cialis?
Both contain tadalafil, but Tadalista Professional is marketed only as a 20mg on‑demand tablet, whereas Cialis is available in daily low‑dose forms and a range of on‑demand strengths (10mg, 20mg). The branding and packaging also differ, which can affect perceived discretion and pricing.
Will Tadalista Professional cause priapism?
Priapism (an erection lasting longer than 4hours) is rare-less than 1% of users-but it can happen if the drug is taken with other PDE5 inhibitors or high doses. Seek medical help immediately if it occurs.
Can I buy Tadalista Professional without a prescription in the UK?
No. UK law requires a prescription for any tadalafil product, including Tadalista Professional. Some online pharmacies claim otherwise, but they risk legal penalties and counterfeit risk.
By matching your lifestyle, health profile, and budget to the right pill, you’ll get the confidence you need without unnecessary hassle. If you’ve narrowed down your choice, talk to your GP and let them know you’ve done the homework-most clinicians appreciate an informed patient.